Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study
نویسندگان
چکیده
منابع مشابه
Mass treatment with single-dose azithromycin for yaws.
BACKGROUND Mass treatment with azithromycin is a central component of the new World Health Organization (WHO) strategy to eradicate yaws. Empirical data on the effectiveness of the strategy are required as a prerequisite for worldwide implementation of the plan. METHODS We performed repeated clinical surveys for active yaws, serologic surveys for latent yaws, and molecular analyses to determi...
متن کاملImpact of Community Mass Treatment with Azithromycin for Trachoma Elimination on the Prevalence of Yaws
BACKGROUND Community mass treatment with 30 mg/kg azithromycin is central to the new WHO strategy for eradicating yaws. Both yaws and trachoma--which is earmarked for elimination by 2020 using a strategy that includes mass treatment with 20 mg/kg azithromycin--are endemic in the Pacific, raising the possibility of an integrated approach to disease control. Community mass treatment with azithrom...
متن کاملCommunity-based mass treatment with azithromycin for the elimination of yaws in Ghana—Results of a pilot study
INTRODUCTION The WHO yaws eradication strategy consists of one round of total community treatment (TCT) of single-dose azithromycin with coverage of > 90%.The efficacy of the strategy to reduce the levels on infection has been demonstrated previously in isolated island communities in the Pacific region. We aimed to determine the efficacy of a single round of TCT with azithromycin to achieve a d...
متن کاملMass treatment with single-dose azithromycin for trachoma.
BACKGROUND Trachoma, caused by repeated ocular infection with Chlamydia trachomatis, is an important cause of blindness. Current recommended dosing intervals for mass azithromycin treatment for trachoma are based on a mathematical model. METHODS We collected conjunctival swabs for quantitative polymerase-chain-reaction assay of C. trachomatis before and 2, 6, 12, 18, and 24 months after mass ...
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ژورنال
عنوان ژورنال: The Lancet
سال: 2018
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(18)30204-6